Determination of the Contents in Compound Furacilin Nasal Drops by RP-HPLC / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-519313
ABSTRACT
OBJECTIVE:
A RP-HPLC method to determine the contents of furacilin and ephedrine hydrochloride in compound furacilin nasal drops was establishedMETHODS:
Chromatographic detection was performed with a mixture of methanol-water-triethylamine-acetic acid(12∶88∶0 2∶1) as mobile phase and Kromasil C18(4 6mm?250mm,5?m) as separate column Chloramphenicol was selected as internal standard and the detection wavelength was 254nmRESULTS:
The ingredients of compound furacilin nasal drops and internal standard were well separated within 18min Good linearities and recoveries for furacilin and ephedrine hydrochloride were obtained in their assay rangesCONCLUSION:
The RP-HPLC method was found to be simple,accurate and suitable for the quality control of compound furacilin nasal drops
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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