Effect of carbon monoxide on permeability of brain blood barrier in cerebral local ischemia rats / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-519372
ABSTRACT
AIM:
To evaluate the effect of carbon monoxide(CO) on the permeability of brain blood barrier(BBB) in cerebral ischemic rats.METHODS:
SD rats were divided into three groups. Saline, hemin or ZnPP were injected intraperitoneally 12 h before middle cerebral artery occlusion (MCAO), respectively. The concentration of blood CO and the permeability of BBB at 24 h after MCAO were measured.RESULTS:
The CO concentration in blood in hemin group was higher than that in saline group( P 0.05).CONCLUSION:
CO reduced the permeability of BBB as a messenger gas molecular when its intrinsic concentration was elevated.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
2000
Type:
Article
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