Expression of Endothelin-1 and Endothelial Nitric Oxide Synthase Gene in Placental Villus in Preeclampsia / 中华围产医学杂志
Chinese Journal of Perinatal Medicine
;
(12)1998.
Article
in Chinese
| WPRIM
| ID: wpr-519597
ABSTRACT
Objective To study the expression of endothelin-1(ET-1) and endothelial nitric oxide synthase(eNOS) mRNA in the villus of pre-eclampsia and the effect of the ET-1 and eNOS on umbilical artery flow velocity wareforms. Methods Dot blotting, DIG-labeled human ET-1 and eNOS cDNA probes were used to examine the expression of the ET-1 and eNOS gene in the placental villus tissues of women with normal gestation and pre-eclampsia. Leica QWIN image disposal and analysis system were used to assess the mean OD of every dot. Colour doppler was used to examine the umbilical artery flow the day before childbirth. Results The level of ET-1 mRNA in placental villus was significantly higher in pre-eclampsia group than the normal group(0.43?0.03 versus 0.23?0.44,P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Perinatal Medicine
Year:
1998
Type:
Article
Similar
MEDLINE
...
LILACS
LIS