G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health
Journal of Menopausal Medicine
;
: 79-81, 2015.
Article
in English
| WPRIM
| ID: wpr-51973
ABSTRACT
Estrogen - the female sexual hormone playing the most important role - plays a physiologically significant role, not only regulating in cell signals with second messenger but also being active in regulating transcription. Estrogen receptor (ER) which is a protein accepting estrogen not only play the role of a transcription factor combining with other genes to regulate their activity like other nuclear receptors but also performs external activities, combining with DNA, etc. G-protein coupled ER (GPER) that has been recently discovered exists as 7-membrane and has non-genomic (rapid) signaling. These functions, however, are not extensively addressed. This paper discusses the roles of GPER and its physiological mechanism.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Transcription Factors
/
DNA
/
Second Messenger Systems
/
Women's Health
/
Receptors, Cytoplasmic and Nuclear
/
GTP-Binding Proteins
/
Genomics
/
Estradiol
/
Estrogens
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Menopausal Medicine
Year:
2015
Type:
Article
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