Simultaneous Determination of Chloromycetin and Dexamethasone Acetate in Jiefu Cream by HPLC / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-519747
ABSTRACT
OBJECTIVE:
To determine the contents of chloromycetin and dexamethasone acetate in Jiefu cream.METHODS:
A reversed-phase HPLC was established for the determination with C18 column as stationary phase.The mobile phase consisted of acetonitrile and 0.05%mol/L phosphate buffer solution(40∶60),the detection wavelength was 240nm.RESULTS:
Chlorom-ycetin had a good linearity (r=0.9 998) in the range of 0.1~0.3mg/ml,the mean recovery was 100.6% with a RSD of 1.3%.Dexamethasone acetate had a good linearity(r=0.9 998) in the range of 0.02~0.08mg/ml,the mean recovery was 101.1% with a RSD of 1.7%.CONCLUSION:
The method is simple,sensitive and accurate.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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