Clinical Observation on the Safety and Efficacy of Wonderful in the Treatment of Genital Herpes / 中国药房

ABSTRACT

OBJECTIVE:To assess clinical efficacy and safety of Wonderful(W),a preparation of polysaccharides of rhizoma polygonati,in the treatment of genital herpes(GH).METHODS:In a random,open,parallel and controlled design,400 cases of GH were divided into 5 groups(each group 80 cases)open W spray(WS) group,open W cream(WC) group,parallel WS group,parallel WC group and control group(aciclovir ointment AO).The therapeutic efficacy and ADRs were observed.RESULTS:The total effective rates of open WS group,parallel WS group,open WC group and parallel WC group were 92.50%,91.25%,93.75% and 91.25% respectively.Effects showed in 64.38% of cases treated with WS(open+parallel) and 68.13% of cases treated with WC within 3 days and 91.88% and 91.88% within 7 days.The initiation of effect of W was 2 days earlier than that of AO.No serious ADRs were found and the patients' compliance was good.CONCLUSION:W is rapid in initiation of efficacy,short in therapeutic course,satisfactory in effect,convenient in application and safe.