Comparison of Six Methods Ameliorating the Disintegration of Calcium Citrate Tablet / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-519909
ABSTRACT
OBJECTIVE:
To compare severalMETHODS:
ameliorating the disintegration of calcium citrate tablet .METHODS:
To prepare calcium citrate tablet by six differentMETHODS:
and to determine and evaluate the prepared tablet in respect to the apperance,difference in weight of tablets,hardness,friability and stability .RESULTS:
The disintegration was not significantly ameliorated by increasing disintegrant or decreasing lubricant .The hardness was decreased and the friability was increased by decreasing the amount of binder or adding more disintegrant or crushing calcium citrate to powder.The two latterMETHODS:
increased the difference in weight of tablets.CONCLUSION:
The optimal method to ameliorate the disintegration is to diminish the grain diameter and the other parameters of quality is able to be up to the standard.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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