Protective Effect of Renal Function from Damage Due to ESWL by Nifedipine Controlled-release Tablet / 中国医师杂志

ABSTRACT

Objective To study the protective effect of nifedipine controlled release tablet on renal function from damage due to extracorporeal shock wave lithotripsy(ESWL).Methods 93 cases of renal stone underwent extracoporeal shock wave lithotripsy(ESWL) were randomly divided into 2 groups,the adalat gits group (n=56)and the control group(n=37).In the former group ,adalat gits was given 30mg once a day for 3 days before ESWL and 1 days after ESWL, but in the control group did not take any drug.Urinary albumin, immunoglobulin-G, ? 2-microglobulin and Thmm-Horsfall protein were assayed to evaluate the renal function.Results In the control group,ALB, lgG and ? 2-MG showed a significant increased(P0 05).Conclusions Adalat gits could protect the renal function from damage due to ESWL.