Screening the Formulae of Norfloxacin Zinc Granules Using Uniform Design / 中国药房
China Pharmacy
;
(12)1991.
Article
in Chinese
| WPRIM
| ID: wpr-520342
ABSTRACT
OBJECTIVE:
To screen the formulae of norfloxacin zinc(NF-Zn) suspended granules using uniform designMETHODS:
The uniform design with 5 levels and 4 factors was employed to screen five formulae of NF-Zn and sedimentation rate,granularity,dissolubility,moisture content and taste of these granules were evaluated and scored The total score of each formula was regressed with the 4 factors by computerRESULTS:
The results of regression equation suggested that the optimum formula was NF-Zn 0 2g,CMS-Na 0 25g,2%PVP and manitol 0 55g in each packetCONCLUSION:
It is effective and convenient to optimize the formula of NF-Zn granules by uniformdesign:
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Screening study
Language:
Chinese
Journal:
China Pharmacy
Year:
1991
Type:
Article
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