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The relationship between expression of ?_3 integrin, focal adhesion kinase and migration of vascular smooth muscle cells stimulated by extracellular matrix / 中国病理生理杂志
Chinese Journal of Pathophysiology ; (12)1986.
Article in Chinese | WPRIM | ID: wpr-520409
ABSTRACT

AIM:

To study the relationship between expression of ? 3 integrin, focal adhesion kinase (FAK) and migration of vascular smooth muscle cells (VSMC) stimulated by osteopontin (OPN) and fibronectin (FN).

METHODS:

VSMC migration was examined using a model of wounding injury of confluent cultured cells. The expression of ? 3 integrin, FAK and Gax genes in VSMC were detected using Western blotting and RT-PCR.

RESULTS:

OPN and FN induced the migration activity of VSMC in a time-dependent manner ( P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pathophysiology Year: 1986 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pathophysiology Year: 1986 Type: Article