Determination of Concentration of Cefixime in Human Serum by RP-HPLC / 中国药房
China Pharmacy
; (12)1991.
Article
in Zh
| WPRIM
| ID: wpr-520474
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:To establish a RP-HPLC method to determine concentration of cefixime in human serum.ME_ THODS:The assay was conducted on Agilent ZORBAX?SB C 18 column with methanal-water-PBS(25∶15∶60,V/V/V)as mobile phase.The detection wavelength was270nm,and the acetanilide was taken as internal standard.RESULTS:The lin?earity range was0.11~5.28mg/L with a regressive equation of Y-0.07534X-0.13186,r=0.9995.The recovery was high.CONCLUSION:This method is accurate,rapid and simple and can be used for determining the concentration of cefixime in human serum.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
1991
Type:
Article