Expression of Vascular Endothelial Growth Factor and nm23 Proteins and Microvessel Density in Hepatocellular Carcinoma and Their Relation With Metastasis / 中国医师杂志

ABSTRACT

Objective To investigate expressions of vascular endothelial growth factor (VEGF) and nm23 proteins and microvessel density in HCC,simultaneously,their relation with metastasis was also studied.Methods The expression of VEGF and nm23 and CD34 protein in 56 HCCs were detected by immunohistochemical technique.Results Of 56 HCCs, the intensity of VEGF expression in HCCs with metastasis was significantly higher than that in HCCs without metastasis (P