Effects and Clinical Significance of Angelica Sinensis Injection on the Functional State of Platelet in Patients With Ulcerative Colitis / 中国医师杂志

ABSTRACT

Objective To study the effects of the effective composition of Angelica sinensis injection on the functional state of platelet in patients with ulcerative colitis (UC),and its significance of therapy.Methods In 64 patients with UC and 30 healthy people, a-granule membrane protein (GMP-140), thromboxane B 2(TXB 2), 6-keto-PGF 1a were detected by means of ELISA.Platelet adhesion rate was detected by the platelet adhesion meter, von willebrand faetor related antigen (vWFAg) was also detected by the means of monoclonal -ELISA.Results The indexes of platelet activation and vWFAg in patients with UC were significanrly higher than those in the control group (P