Preparation of Fluconazole-?-Cyclodextrin Inclusion Complex / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-521009
ABSTRACT
OBJECTIVE:
To study the preparation technic and determination of the content and dissolubility of the fluconazole-?-cyclodextrin inclusion complex(FCIC)METHODS:
The FCIC was prepared by coprecipitation method and ultr_asonic method The content and percentage of the accumulated dissolubility of FCIC were determined by UV-spectrophotometryRESULTS:
Fluconazole and ?-cyclodextrin could form inclusion complex through either preparation technology The contents of fluconazole in the complex were(11 34?0 77)% and(11 23?0 24)% respectively The dissolubility met the standard in CPCONCLUSION:
Stable complex could be formed between fluconazole and ?-cyclodextrin
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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