Preparation of FLX-TNZ Hollow Effervescent Suppository / 中国药房

ABSTRACT

OBJECTIVE:To establish the preparation technic and method of qualit y control of fleroxacin-tinidazole(FLX-TNZ)hollow effervescent suppository METH ODS36-type semi-synthetic aliphatic ester was used as base material and doub le-wavelength UV-spectrophotometry was adopted for determination of the conten ts of fleroxacin and tinidazole RESULTS:The average recovery rates(n=5)of fler oxacin and tinidazole were 99 72% and 99 08%,while RSDs were 0 95% and 1 02% respectively CONCLUSION:This method has a sound design and feasible tec hnnology