Effect of cGMP on voltage-gated potassium channel in pulmonary artery smooth muscle cells from rats exposed to chronic hypoxia

Yongchang ZHANG; Wang NI; Guohua ZHEN; Zhenxiang ZHANG; Yongjian XU

Effect of cGMP on voltage-gated potassium channel in pulmonary artery smooth muscle cells from rats exposed to chronic hypoxia / 中国病理生理杂志

Yongchang ZHANG; Wang NI; Guohua ZHEN; Zhenxiang ZHANG; Yongjian XU.

Chinese Journal of Pathophysiology ; (12)2000.

Article in Zh | WPRIM | ID: wpr-521204

Responsible library: WPRO

ABSTRACT

ABSTRACT

0.05]. CONCLUSIONS: The currents of voltage-gated potassium channel was inhibited by chronic hypoxic. The inhibitory effect of cGMP on currents of voltage-gated potassium channel in PASMCs from both normal and chronic hypoxic rats may be probably through the phosphorylation of voltage-gated potassium channel.

Key words

Guanosine cyclic monophosphate; Anoxia; Pulmonary artery; Potassium channels

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Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Journal of Pathophysiology Year: 2000 Type: Article

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Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Journal of Pathophysiology Year: 2000 Type: Article