Expression of costimulatory molecules on peripheral blood lymphocytes in patients with Behet's disease / 中华眼底病杂志
Chinese Journal of Ocular Fundus Diseases
;
(6)2003.
Article
in Chinese
| WPRIM
| ID: wpr-521541
ABSTRACT
Objective To investigate the expression of costimulatory molecules( B7, CD28, and CTLA-4) of peripheral blood lymphocytes in patients with Behcet′s ) disease(BD). Methods Lymphocytes were obtained in 24 patients with BD and 20 healthy individuals, and the expression of CD80(B7-1), CD86(B7-2), CD28 and CTLA-4 on T and B cells were detected by direct three-color immunofluorescence flow cytometry. Results Significantly increased expression of CTLA-4 on CD4 + T cells [(3. 18?1. 18)%] was found in BD patients compared with that in controls [(1. 73?0. 66) %] ( t=-3. 722,P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Ocular Fundus Diseases
Year:
2003
Type:
Article
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