Endoscopic mucosal resection of gastrointestinal tract tumor / 中华消化内镜杂志

ABSTRACT

Objective To investigate neoplastic lesions in gastrointestinal tract treated by endoscop-ic mucosal resection (EMR). Methods The properties, extent and infiltrating depth of the neoplastic lesions in gastrointestinal tract were detected by chromoendoscopy, magnifying videoscopy and endoscopic ul-trasonograpy. The tumors in niucosa or its muscular layer including the early cancer, precancerous lesion, submucosal tumors, polyps in laterally development, large polyps with or without peduncle were removed by EMR or transparent plastic cap EMR. Results Thirty-one submucosal tumors and four early cancers (esoph-ageal cancer 2, cardiac carcinoma 1 , early colonic carcinoma 1 ) and moderate or severe gastric dysplasia 2 were treated by EMR or transparent plastic cap EMR, no recurrence happened within 3-18 months follow-up. Laterally spreaded 13 polyps and 21 subpedunculated or sessile typed large polyps were resected by the procedures of EMR and Endoscopic Piecemeal Mucosal Resection ( EPMR). Five (7. 04% ) cases were complicated with bleeding during the procedure, and cured under endoscopies. One patient with villus adenoma ( 1. 41% ) recurred three months after EMR. Conclusion Under the guidance of chromoendoscopy, magnifying videoscope and endoscopic ultrasoundgraphy, EMR is a safe and effective endoscopic therapy for early cancers, submucosal tumors and large polyps in gastrointestinal tract.