Protective Effect of Combination of Xingnaojing and Ligustrazine on Rat's Cortical Neurons of Primary Culture / 中国药房
China Pharmacy
;
(12)1991.
Article
in Chinese
| WPRIM
| ID: wpr-522127
ABSTRACT
OBJECTIVE:
To study the protective effects of Xingnaojing(XNJ)and Ligustrazine(Lig)on rat's cortical neu_ rons of primary culture.METHODS:
The effects of XNJ and Lig in counteracting the excitotoxicity of glutamic acid(10?l/L,3h)in rat's cortical neurons of primary culture were observed.RESULTS:
Both XNJ and Lig could decrease the release of LDH from cells into culture medium and reduce the changes in cell morphology.CONCLUSION:
XNJ or Lig can protect cultured cortical neurons from excitotoxicity of glutamic acid and more obvious effect can be initiated through combined use of them.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
1991
Type:
Article
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