Effect of Polygonum Multiflorum Thunb on Learning-memory Ability in Rats with Alzheimer Disease and Its Probable Mechanism / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-522230
ABSTRACT
Objective To study the effect of Polygonum Multiflorum Thunb(PMT) on learning-memory ability in rats with Alzheimer disease(AD) and its probable mechanism. Metheds Rats were trained by Y-maze and were detected its learning-memory ability before the rats received the injection of A?1-40. The rats were treated with different dosage of PMT after the model of AD was set up. The learning-memory ability and the levels of superoxide dismutase (SOD) and malondialdehyde(MDA) were detected. Results Compared with model rats, the rats treated by middle and high-dosage of PMT, the learning-memory ability of was better,the SOD activity of was higher and the MDA concentration of was lower (P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2001
Type:
Article
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