Preparation and Quality Control of Compound Fuyankang Suppository / 中国药房

ABSTRACT

OBJECTIVE: To prepare the compound Fuyankang suppository and establish the quality controlmethod. METHODS:Funancillin and Tinidazole were used to prepare compound Fuyankang suppository and HPLC method was established for content determination of funancillin and Tinidazole in the suppository .RESULTS: The standard curves of fu-nancillin and Tinidazole were linear in the ranges of (9.6672-22.5 568)?g/ml(r = 0.9 998, n = 5) and (192.048-448.112) ?g/ml(r = 0.9 999,n= 5)and the average recoveries were 101.45% and 100.37% with RSD 1.771%(n= 5) and 1.177%(n = 5) respectively .CONCLUSION: The suppository is stable in quality.The method of determination of the contents is simple, rapid and reliable.