Dynamical Observation of Peak Pressure of Tympanogrom Before and After Radiotherapy for Nasopharyngeal Carcinoma / 听力学及言语疾病杂志

ABSTRACT

Objective To explore the changes of the peak pressure of tympanogrom in the first year before and after radiotherapy for Nasopharyngeal Carcinoma (NPC) and observe its effect to audition.Methods Acoustic immittance and audiometry were used to detect 64 ears of NPC patients at regular intervals (before, during,at the end of rediotherapy and 6,12 months after radiotherapy). The data were collected and analyzed with statistic methods. Results There were 9 ears with secretory otitis media after radiotherapy. The peak pressure of tympanogrom of other 55 ears was negative at the beginning of radiation, reached highest at the end of radiotherapy,the average was -30(-100, 5.0) daPa.Compared with the peak pressure of tympanogrom before radiation, there was significant statistic difference ( P =0.001). The peak pressure reached to the level of pre-radiation 12 months after radiation, 5.0(-2.5,10.0) daPa. The 2.0 kHz audiometric threshold of bone conduction was 21.4?5.7 dB in 55 ears, compared with the audiometric threshold before radiation, there was evident statistic difference (P