Expression of Collagenase Ⅳ and Collagen Type Ⅳ in Papillary Thyroid Carcinoma / 中国医师杂志

ABSTRACT

Objective To study the expression of collagenase Ⅳ and collagen type Ⅳ in papillary thyroid carcinoma (PTC). Methods Immunohistochemical staining(SP method)was used to detect the expression of collagenase Ⅳ and collagen typeⅣ. Results ⑴The positive expression rate of collagenase Ⅳ was 77 9%, 66 7%, 80 0%, 88 9% and 25 4% in PTC, papillary microcarcinoma, intra-thyroid, extra-thyroid carcinoma and tissues adjacent to tumor(P