Effects of Glucocorticoid Therapy on Bone Mineral Density in the Patients with Glumerulose Disease / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-522736
ABSTRACT
Objective To investigate the effects of long-term glucocorticoid therapy on bone mineral density(BMD) in the patients with glumerulose disease. Methods 41 patients with glumerulose disease were prospectively studied. The BMD of lumbar spine (L 2-4 ) and femur was measured using dual-energy X-ray absorptiometry at base line, and at every 3 to 6 months interval after receiving glucocorticoid therapy. Vitamin D receptor (VDR) gene polymorphism was detected using PCR-RFLP. Results ⑴ Every measured site BMD decreased(29 9~83 8)mg/cm 2 after 15-month administration of glucocorticorids, and BMD decrease in L 2-4 and femoral trochanter was significantly greater (P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2001
Type:
Article
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