The role of autoantibodies against angiotensin Ⅱ type 1-receptor in the pathogenesis in preeclampsia / 中华围产医学杂志
Chinese Journal of Perinatal Medicine
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-523002
ABSTRACT
Objective To explore the role of the autoantibodies against angiotensinⅡ type 1 receptor (ATR-1) in the pathogenesis of preeclampsia. Methods Forty normotensive and 46 pregnant women with preeclampsia were recruited in this study. Synthesized ATR-1 polypeptide fragment was used as antigens to screen the autoantibodies against ATR-1 by ELISA. The level of angiotensinⅡ was also examined. Results The positive rate of the ATR-1 antibodies and plasma level of angiotensin Ⅱ in patients with preeclampsia [63.0%(29/46) and (92.54?37.22) pmol/L] were significantly higher than those in normotensives [7.5% (3/40) and (25.75?12.33) pmol/L, P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Perinatal Medicine
Year:
2000
Type:
Article
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