The establishment of a nude mouse model of intrahepatic implantation of human liver carcinoma tissue with unchanged tumor biologic features / 中国普通外科杂志

ABSTRACT

0.05). Second and third generation of the implanted tumor were obtained in 8 nude mice respectively,and all transplanted tumors survived. Liver,bone and lung metastasis were found in 100% of nude mice between 10 w～14 w. [WT5”HZ] Conclusions This nude mouse HCC model holds the biologic features of human HCC and serves the purpose of in vivo study investigation .