Cost-effectiveness Analysis of Three Pharmacotherapeutic Schemes for Essential Hypertension / 中国药房

ABSTRACT

OBJECTIVE:To evaluate the3pharmacotherapeutic schemes for essential hypertension by pharmacoeconomic method.METHODS:143out-patients with essential hypertension were randomly divided into3groupsgroup A(n=47)re?ceived Losartan K50mg q.d.;group B(n=48)Captopril25mg b.i.d.;group C(n=48)Losartan K50mg q.d.+Hy?drochlorothiazide25mg q.d..All3groups were treated for4weeks and the effects and ADRs were observed,data was evaluated with the pharmacoeconomic cost-effectiveness analysis method.RESULTS:The effective rate of group C was markedly higher than those of other two groups(P0.05),and group C was also the lowest in C/E and?C/?E.CONCLUSION:Scheme C is the best one.