Separation of Cefuroxime Enantiomers by Capillary Zone Electrophoress / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-523558
ABSTRACT
OBJECTIVE:
To develop a method for separating the cefuroxime enantiomers by capillary zone electrophoresis(CZE).METHODS:
Melting capillary column(570mm?75?m)was used with0.04mmol/L hydroxypropyl-?-cyclodextrin and37.5mmol/L NaH 2 PO 4 as buffer solution(pH=6.0).The operation voltage was15kV;temperature was25℃;detecting wavelength was280nm and pressure injection was performed at5kPa for6seconds.RESULTS:
The total time for separation and determination was within10min.The recovery was90%~106%.CONCLUSION:
This method is simple and rapid,and can be used to determine the content of cefuroxime enantiomers in cefuroxime powder for injection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS