Effect of Supplemented Four Agents Decoction Formula on Cell Prolifer ation and the Expression of Tyrosinase and c-kit Genes in Melanocytes In Vitro / 中华皮肤科杂志

ABSTRACT

0.05). However, this medicine significan tly enhanced c-kit expression in melanocytes in vitro with an increase of 79.41% . Conclusions The efficacy of supplemented four agents decoction formula in th e treatment of vitiligo may be related to the SCF (stem cell factor)/c-kit pathw ay. This Chinese traditional medicine may enhance c-kit expression, but may not be associated with cell proliferation and Tyr expression of melanocytes.