A Case of Kaposi's Sarcoma Improved by Sirolimus Treatment in the Kidney Transplant Recipient / 대한신장학회지
Korean Journal of Nephrology
;
: 82-87, 2009.
Article
in Korean
| WPRIM
| ID: wpr-52376
ABSTRACT
The incidence of Kaposi's sarcoma (KS) increases in kidney transplant recipients who had the immunosuppressive therapy. The usual treatment of KS is to reduce the dosage of immunosuppressive agents, with chemotherapy and/or radiotherapy. Several studies have recently demonstrated that the conversion to proliferation signal inhibitors (PSIs) from calcineurin inhibitors (CNI) leads to the remission of some post-transplant tumors such as KS. PSIs were well tolerated with stable renal function and no episode of acute rejection was reported. On the basis of these findings, we report a case of Kaposi's sarcoma in the kidney transplant patient, who had multiple lymphadenopathy and hepatic involvement without skin lesions. This patient responded well to the change of the immunosuppressive treatment from cyclosporine to sirolimus, one of PSIs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rejection, Psychology
/
Sarcoma, Kaposi
/
Skin
/
Incidence
/
Kidney Transplantation
/
Cyclosporine
/
Calcineurin
/
Transplants
/
Sirolimus
/
Immunosuppressive Agents
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2009
Type:
Article
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