Expression level of JT8 gene decreases in coronary artery disease / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)2000.
Article
in Chinese
| WPRIM
| ID: wpr-523826
ABSTRACT
AIM:
To confirm the expression level of the gene which corresponding to JT8 tag decreased in coronary artery disease (CAD).METHODS:
The validity and reliability of the results gotten by serial analysis of gene expression method was verified by RT-PCR and Northern blot. The expression level of the gene which corresponding to JT8 tag was compared with the expression level of GAPDH and ?-actin in JT and WY, while according to SAGE results that the gene expression level of JT8 gene was 8 times higher in JT than in WY.RESULTS:
It was found that the results of RT-PCR and Northern bolt were identified with the results of SAGE. The expression level of JT8 gene decreased in CAD.CONCLUSION:
These results verified the validity of SAGE method and made a good foundation for further discovery of new candidate genes. [
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
2000
Type:
Article
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