Determination of Two Ingredients in Calamine and Menthol Lotion by GC-MS / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-523854
ABSTRACT
OBJECTIVE:
To establish a GC-MS assay for determination of the contents of phenol and menthol in calamine and menthol lotion.METHODS:
Using DM-5elastic quartz capillary as separation column,I-octanol as internal standard,phenol and menthol were detected separately under the70℃~150℃step-up hyperthermic condition to select the ion fragment peaks with M/Z of94and71.RESULTS:
Phenol and menthol were good linear within1.092~21.840?g/ml(r=0.9998)and1.194~9.552?g/ml(r=0.9999).Recoveries were100.2%(RSD=1.34%)and100.4%(RSD=0.74%)respective?ly.CONCLUSION:
The method is quick and accurate with highly repeatability and specificity and it is adequate for contents determination and quality control for this preparation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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