A Study on the Effect of IL-2 Therapy on Chemotherapeutic Sensitivity in Hepatocelluar Carcinoma / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-524009
ABSTRACT
Objective To investigate the relationship between the interleukin-2 (IL-2) treatment and chemotherapeutic sensitivity in hepatocellular carcinoma (HCC). Methods S-P immunohistochemical staining was adopted to determine the expression of multidrugs resistance-associated protein(MRP1) and IL-2 receptor ? chain in paraffin embedded HCC tissues of the patients treated with and without IL-2. Results The expression level of IL-2 receptor ?-chain in HCC tissues of the patients treated with and without IL-2 was 0.301 9?0.040 23 and 0.263 1?0.022 24, respectively, which had significant difference between the two kinds of HCC tissues. The expression level of MRP1 in the HCC tissues of the patients treated with IL-2 (0.336 4?0.044 67) was markedly higher than that in HCC tissues of the patients treated without IL-2 (0.300 8?0.037 64,t=2.176,P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2001
Type:
Article
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