Role of PKC and MMPs in the pathogenesis of the rat experimental atherosclerosis and the action of Danshen injection / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-524066
ABSTRACT
AIM:
To study the effects of protein kinase C on the expression of MMPs that may play an important role in the formation of atherosclerosis and the possible mechanism of Danshen injection to treat atherosclerosis.METHODS:
50 Sprgue-Dawley (SD) rats were divided into three groups randomly control group (group C), model group (group M) and Denshen treatment group (group D). The serum was collected to measure the level of cholesterol, triglyceride, low density lipoprotein cholesterol(LDL-ch). The expression of PKC and MMPs were measured by immunohistochemistry. Light microscope and electron microscope were also used.RESULTS:
① The cholesterol, triglyceride, LDL-ch concentrations in group M and group D were significantly higher than those in group C (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1986
Type:
Article
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