Study on the Restraining Factors in the Intravenous Immune Globulin(IVIG)Bacterial Endotoxin Test / 中国药房
China Pharmacy
;
(12)1991.
Article
in Chinese
| WPRIM
| ID: wpr-524294
ABSTRACT
OBJECTIVE:
To study the restraining factors in the intravenous immune globulin(IVIG.)bacterial endotoxin test.METHODS:
A series tests were designed;the sensitivity of limulus was checked and the limit of endotoxin was validated;the effects of vehicle and pH value on the IVIG endotoxin test results were observed so as to find out the chief restraining factors of this test method.RESULTS:
Lower pH value has an inhibition effect on the in IVIG bacterial endotoxin test.CONCLUSION:
Bacterial endotoxin test can replace the rabbit testing method in the pyrogen test of IVIG.When the condition of lower pH is changed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
1991
Type:
Article
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