Study on the Anti-oxidative Action of Melatonin on the Oxidative Damage Model of Brain Tissues of Mice / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-524522
ABSTRACT
OBJECTIVE:
To study the counteraction of melatonin(MT)on the oxidative damage model of brain tissues of mice caused by glutamic acid.METHODS:
The mice were randomly divided into blank group,model group and melatonin(MT)(high dosage and low dosage)group.Drugs were injected(by intraperitoneal injection)into the mice of the MT group in advance for7days.Each group were injected with glutamic acid through lateral ventricle to form models,levels of MDA and GSH and the activity of GSH-PX of each group were determined.RESULTS:
There was a significant increase in the level of MDA(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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