Expression and Significance of Cyclooxygenase-2 in Cervical,Endometrial and Ovarian Cancers / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-524574
ABSTRACT
Objective To study cyclooxygenase-2 (COX-2) expression levels in cervical, endometrial and ovarian cancers as well as their originated normal tissues. Methods Semiquantitative immunofluorescent assay (IFA) was used to detect COX-2 expression levels in cervical squamous cell carcinoma (n=12),endometrial adenocarcinoma (n=13),and ovarian serous adenocarcinoma (n=9). COX-2 expression levels in normal cervical (n=14),endometrial (n=15),and ovarian (n=13) tissues were simultaneously detected as control. Results Normal cervical tissues expressed COX-2 more frequently than cervical cancers (50% vs 23%), but the difference was not signicant (P=0.247). The positive rate of COX-2 expression was significantly higher in endometrial adenocarcinomas (69%) than that in normal endometrium (7%) (P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2001
Type:
Article
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