Role of the Duodenum on Sphincter of Oddi Motility in Conscious Dogs / 中华肝胆外科杂志

ABSTRACT

Objective The aim of the present study was to determine the role of the duodenum in controlling sphincter of Oddi(SO) motility using conscious dogs after total duodenectomy. Methods In a control group (n=6), a cannula was implanted into the duodenum opposite to the papilla to allow sphincter of Oddi manometry. In a duodenectomy group (n=6), the papillae were preserved at total duodenectomy and sutured to the jejunum anastomosed to the stomach (neoduodenum). The cannula was implanted opposite to the implanted papillae. Interdigestive and postprandial sphincter of Oddi and duodenal or neoduodenal motility were recorded by manometric and myoelectric methods. Results Duodenectomy disrupted SO cyclic motility. Conclusions During the interdigestive period, the duodenum has a distinct role in regulating sphincter of Oddi cyclic motility.