Study on the Drug-releasing of Aciclovir Eye Gel in Vitro / 中国药房

ABSTRACT

OBJECTIVE:To study the drug-releasing characteristics of acyclovir eye gel in vitro.METHODS:The buffer phosphate was taken as the releasing mediator,the content of the aciclovir in the releasing mediator was determined by HPLC,the drug releasing charactersitic of aciclovir eye gel was studied by bag filter method.RESULTS:The releasing curve of the aciclovir eye gel in vitro was in line with the first-order drug releasing equation.CONCLUSION:The aciclovir eye gel is characterized by slow-release to some degree.