Multiple Ruptured Cerebral Aneurysms as a Presenting Feature of Pheochromocytoma in a Patient with Neurofibromatosis 1 / 대한내과학회지
Korean Journal of Medicine
;
: 327-330, 2015.
Article
in English
| WPRIM
| ID: wpr-52496
ABSTRACT
Neurofibromatosis 1 (NF-1) shows an autosomal dominant pattern of inheritance with complete penetrance and variable expression. Vascular abnormalities are frequently associated with NF-1. Pheochromocytoma occurs in 0.1-5.7% of patients with NF-1. Spontaneous intracerebral hemorrhage in patients with NF-1-related pheochromocytoma is very rare. Herein, we report a case of subarachnoid hemorrhage caused by multiple ruptured cerebral aneurysms in a patient with concurrent NF-1 and pheochromocytoma. Coil embolization of the aneurysms and subsequent adrenalectomy for pheochromocytoma were successfully performed, and the patient remained normotensive thereafter. This case demonstrates the importance of a careful search for a remediable cause of episodic hypertension in patients with NF-1, who are predisposed to cerebral hemorrhage from fluctuating blood pressure.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pheochromocytoma
/
Subarachnoid Hemorrhage
/
Wills
/
Blood Pressure
/
Intracranial Aneurysm
/
Cerebral Hemorrhage
/
Neurofibromatosis 1
/
Neurofibromatoses
/
Adrenalectomy
/
Penetrance
Limits:
Humans
Language:
English
Journal:
Korean Journal of Medicine
Year:
2015
Type:
Article
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