Determination of Principal Components in Levofloxacin Hydrochloride Ointment by HPLC / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-525106
ABSTRACT
OBJECTIVE:
To establish a HPLC method for the determination of levofloxacin hydrochloride in the levoflo_ xacin hydrochloride ointment.METHODS:
The chromatographic column was C 18 ,the mobile phase was consisted of0.05mol/L citric acid-acetonitrile(85∶15)with detection wavelength at293nm and flow speed at1.0ml/min,the column temperature was40℃and the sample size was10?l.RESULTS:
Good linear relation was achieved when the levofloxacin hydrochloride concen-tration was at the range of3.88~37.88ug/ml(r=0.9998);The average recovery was99.4%(n=9).CONCLUSION:
This determination method is accurate,reliable and it can act as an effective quality control for levofloxacin hydrochloride ointment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS