Simultaneously Content Determination of Camphor and Mentholum in Steam Inhalant by GC / 中国药房

ABSTRACT

OBJECTIVE:To establish a GC method for simultaneously content determination of camphor and mentholum in steam inhalant.METHODS:The glass packed column coated with10%PEG-20mol/L was used,the column temperature was set at120℃,the injection site temperature was160℃,the detector temperature was250℃,the carrier gas was nitrogen of high purity,the flow rate was50ml/min.RESULTS:The detected concentrations of camphor and mentholum showed a good linear correlation in the ranges of0.016～0.176mg/ml(r=0.9998)and0.04～0.44mg/ml(r=0.9999)respectively,the average recoveries were100.27%(RSD=0.79%)and100.18%(RSD=1.11%)respectively.CONCLUSION:The present method is convenient,accurate and sensitive,good resolution which can be used in simultaneously quantitative determination of camphor and mentholum in steam inhalant.