Preparation and Quality Control of Compound Levofloxacin Zinc Cream / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-525597
ABSTRACT
OBJECTIVE:
To prepare compound levofloxacin zinc cream and establish its quality control.METHODS:
Levofloxacin zinc was made from levofloxacin and zinc sulfate,the cream was prepared by adding ground-substance to levofloxacin zinc;The content of levofloxacin was determined by ultraviolet spectrophotometry with the wavelength set at293nm.RESULTS:
The prepared cream was even,fine and easy to spread;The calibration curve of levofloxacin was linear in the range of2~10?g/ml(r=0.9999,n=5),the average recovery rate was99.8%,RSD=0.44(n=5).CONCLUSION:
The formulation of the preparation is reasonable and the preparation technics was simple and feasible,the quality is stable and controllable.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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