The Effect of Hydroxypropyl-?-Cyclodextrin on the Stability of Potassium Dehydroandrographolide Succinate Solution / 中国药房

ABSTRACT

OBJECTIVE:To study the effect of HP-?-CD on the stability of potassium dehydroandrographolide succina_ te solution.METHODS:The stability of the testing group(potassium dehydroandrographolide succinate solution+HP-?-CD)was determined by a thermostatic accelerated test with the content variation of potassium dehydroandrographolide succi?nate solution as an index and the potassium dehydroandrographolide succinate solution that was free of HP-?-CD as the control.RESULTS:The content variation of the testing group was less as against the control group,the terms of validity for the2groups were0.657y and3.40y respectively.CONCLUSION:The stability of potassium dehydroandrographolide succi?nate solution can be increased by adding HP-?-CD to which.