Study of the brain development in infants of diabetic mother / 中华围产医学杂志

ABSTRACT

Objective To study the brain development in infants of diabetic mother. Methods The development of cerebral grey matters and white matters was evaluated in 64 infants of pregnant diabetic mother by echoencephalography and medical image analysis system. The parameters were compared with 101 infants of non-diabetic mother. The early brain response function of newborns was assessed. The neurodevelopment after neonatal period was also evaluated. Results The brain in infants of diabetic mathers was immature.The average values of grey density in thalami (76.92?6.60) were significantly lower in full term infants of diabetic mathers than that of the infants of non-diabetic mathers (84.72?6.35). These were also obvious in white matters of frontal lobe [(62.68?5.21) vs (67.60?4.09)] and occipital lobe [(73.39?5.67) vs (78.61?2.95)] (P