Study on the Compatible Stability of Doxofylline Injection and Dexmethasone Sodium Phosphate Injection / 中国药房

ABSTRACT

OBJECTIVE:To study the compatible stability of doxofylline injection and dexmethasone sodium phosphate injection.METHODS:The changes in appearance and pH value of the mixture of doxofylline injection and dexmethasone sodium phosphate injection in 5%glucose injection within 6 hours at 25℃were observed and determined,the content of which was determined by HPLC.RESULTS:Compared with the solution at 0h of mixing,no significant changes were noted in color,clarity and content within 6 hours' mixing,however,there was an increase in its pH value.CONCLUSION:The mixture of doxophylline and dexmethasone in 5%glucose injection is stable in quality within 6 hours' mixing at 25℃.