Preparation and Quality Control of Compound Ofloxacin Gel / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-525747
ABSTRACT
OBJECTIVE:
To prepare compound ofloxacin gel and to establish its quality control method.METHODS:
Ofloxacin was used as principal agent to be mixed with dexamethasone sodium phosphate,carbomer 940 was taken as base material,the content of ofloxacin and dexamethasone were determined by HPLC method.RESULTS:
The linear detection concentration ranges of ofloxacin and dexamethasone were 20~300?g/ml and 5~50?g/ml,respectively,the average recovery rates of which were (99.8?0.5)%(RSD=0.84%)and (100.6?0.8)%(RSD=0.87%),respectively.CONCLUSION:
The preparation is stable in quality,the prepare technique is simple and the quality control is reliable.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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