Effects of Chlamydia pneumoniae infection and hyperlipidemia on the expression of NF-?B and AP-1 in myocardium / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1999.
Article
in Chinese
| WPRIM
| ID: wpr-525786
ABSTRACT
AIM:
To investigate the effects of Chlamydia pneumoniae infection and hyperlipidemia on the expression of NF-?B and AP-1 in the myocardium.METHODS:
The indirect immunofluorescence method was used to examine wild C57BL/6J mice infected with Chlamydia pneumoniae and fed with an atherogenic diet. The expression of the subunit of NF-?B, P50, and c-Fos in the murine myocardium was observed.RESULTS:
Chlamydia pneumoniae infection and hyperlipidemia induced the activation of NF-?B and AP-1 in murine myocardium. P50 and c-Fos were not detected in the controls, but there were different levels of positive expression in the experiments (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1999
Type:
Article
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