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Do Different Arterial Stiffness Parameters Provide Similar Information in High-Risk Patients for Coronary Artery Disease?
Korean Circulation Journal ; : 819-824, 2013.
Article in English | WPRIM | ID: wpr-52603
ABSTRACT
BACKGROUND AND

OBJECTIVES:

The aim of our study was to compare the values of brachial-ankle pulse wave velocity (baPWV) measured with two different non-invasive methods as predictors of coronary artery disease (CAD) in patients who had undergone coronary angiography. SUBJECTS AND

METHODS:

From 6373 patients who visited our laboratory for non-invasive procedures, we enrolled 965 consecutive patients undergoing coronary angiography. Data for baPWV and peripheral augmentation index (pAI) were recorded. CAD was defined as greater than 50% stenosis of a major epicardial artery in a coronary angiogram. In addition, the severity of CAD was classified as none/minimal or 1-, 2-, or 3-vessel disease, based on previous or current angiographic findings.

RESULTS:

Among 965 subjects, the mean age was 63.7+/-11.6 years, and 58.2% were male. Compared with subjects without CAD disease, those with CAD showed higher values of baPWV (16.6+/-3.5 m/sec vs. 15.9+/-3.4 m/sec, p<0.001), and lower values of pAI (73.5+/-15.9% vs. 76.0+/-15.7%, p=0.01). When the severity of CAD was expressed as none/minimal or 1-, 2-, or 3-vessel disease, there was a significant association between the extent of CAD and baPWV (p<0.001). In univariate analysis, high PWV and low pAI were associated with an increased prevalence of CAD (p<0.001).

CONCLUSION:

Increased baPWV and decreased pAI were associated with the presence of CAD in the elderly.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Arteries / Coronary Artery Disease / Prevalence / Coronary Angiography / Constriction, Pathologic / Coronary Vessels / Vascular Stiffness / Pulse Wave Analysis Type of study: Etiology study / Prevalence study / Prognostic study Limits: Aged / Humans / Male Language: English Journal: Korean Circulation Journal Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Arteries / Coronary Artery Disease / Prevalence / Coronary Angiography / Constriction, Pathologic / Coronary Vessels / Vascular Stiffness / Pulse Wave Analysis Type of study: Etiology study / Prevalence study / Prognostic study Limits: Aged / Humans / Male Language: English Journal: Korean Circulation Journal Year: 2013 Type: Article