Drug - induce Arthralgia: Literature Review of 192 Cases / 中国药房

ABSTRACT

OBJECTIVE: To disscuss the general patterns and characteristics of drug - induced arthralgia. METHODS: The literature of 192 cases with drug- induced arthralgia reported in domestic medicinal journals published from Jan. 1994 to Jun. 2005 were analyzed statistically. RESULTS: The onset of arthrositis occurred in the process of intravenous drip infusion, or a few months, even a few years after the medication. The drugs that induced arthrositis were chiefly antimicrobial drugs, circulation system drugs and digestive system drugs, of which, 110 cases (57.29%) involved the use of pyrazinamide. CONCLUSION: To ensure medication safety, attention should be given to the drug-induced arthralgia for clinical pharmacists.